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In the present paper the researchers have attempted to study the effect of psycho-education as an intervention in increasing clarity among Female Primary Caregivers in handling the Alzheimer’s disease patients and in improving the Quality of care rendered by Female Primary Caregivers for their Alzheimer’s patients. The participants were 10 Female Primary Caregivers of Alzheimer’s disease who resided at home. The Female Primary Caregivers were provided with psycho-education intervention for 10 days. The Alzheimer’s disease Clarity Test [ADCT] was administered to measure Clarity on Theoretical issues of Alzheimer’s disease and Capacity building of female primary caregivers. The Quality of Care Check list was used to observe and measure the presence or absence of care and also record the extent of care in physical and psychological areas received by the patients. The results revealed that the 10 days psycho-education has significantly enhanced the clarity levels among the Female Primary Caregivers after the intervention while, one month psycho-education intervention has to be something continued constantly over a period of time regularly to sustain or retain the effect on caregivers. Therefore, it implies that more the intervention gap then less will be the beneficial effect among the caregivers.