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Being as fit as a fiddle is the utmost importance matter which most of us do not take it seriously. The benefits of physical exercises are hard to ignore, regardless of our age, sex or physical ability. Plus, physical exercise is a great activity to do most during depression especially. Many of us ignore and commonly overlooked it throughout life and prone to eat everything or sleep when in pressure situation. This study aimed to find out does exercise affects depressive symptoms in dental students. It is also to evaluate the effectiveness of physical exercise upon reducing depressive symptoms among them especially and how it influences human nature in them.