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| Published: August 06, 2024
Exploring Brain Receptors: Key Players in Neural Signaling – A Systematic Review
Department of Pharmacology, KLE College of Pharmacy, Rajajinagar, Bangalore, Karnataka, India Google Scholar More about the auther
Department of Pharmacology, KLE College of Pharmacy, Rajajinagar, Bangalore, Karnataka, India Google Scholar More about the auther
Department of Pharmacology, KLE College of Pharmacy, Rajajinagar, Bangalore, Karnataka, India Google Scholar More about the auther
Department of Pharmacology, KLE College of Pharmacy, Rajajinagar, Bangalore, Karnataka, India Google Scholar More about the auther
Department of Pharmacology, KLE College of Pharmacy, Rajajinagar, Bangalore, Karnataka, India Google Scholar More about the auther
DIP: 18.01.082.20241203
DOI: 10.25215/1203.082
ABSTRACT
This review article consists of the functions of opioid receptor binding sites, mainly focusing on mu, kappa, and delta receptors, exemplifying their characters and binding affinities, utilizing a least squares non-linear regression curve fitting program that provides insights on the interaction between opioid and their subtypes. And glutamate receptors particularly the mGlu5 receptor and their role in modulating behaviour and neurobiological responses to substances like amphetamine in preclinical and clinical study. Further of the side effects of cannabis on autism symptoms revealing promising outcomes with observable improvements in various domains and around 4% reported side effects. Overall, this systematic review contains the basic information on all the receptors present in the brain including their subtypes, their location, and function. Information of opioid, glutamate and cannabis receptors in detail.
Keywords
Opioid Receptor, Amphetamine Sensitization, mGlu5, Autism, Cannabinoid
This is an Open Access Research distributed under the terms of the Creative Commons Attribution License (www.creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any Medium, provided the original work is properly cited.
© 2024, Baraka, B.B.H., Khan, A., Pandey, A., Kannur, S. & Porwal, M.
Received: July 25, 2024; Revision Received: August 02, 2024; Accepted: August 06, 2024
Article Overview
ISSN 2348-5396
ISSN 2349-3429
18.01.082.20241203
10.25215/1203.082
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Published in Volume 12, Issue 3, July-September, 2024