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| Published: August 06, 2024

Exploring Brain Receptors: Key Players in Neural Signaling – A Systematic Review

Babiker Bashir Haroun Baraka

Department of Pharmacology, KLE College of Pharmacy, Rajajinagar, Bangalore, Karnataka, India Google Scholar More about the auther

, Alma Khan

Department of Pharmacology, KLE College of Pharmacy, Rajajinagar, Bangalore, Karnataka, India Google Scholar More about the auther

, Abhishek Pandey

Department of Pharmacology, KLE College of Pharmacy, Rajajinagar, Bangalore, Karnataka, India Google Scholar More about the auther

, Sahana Kannur

Department of Pharmacology, KLE College of Pharmacy, Rajajinagar, Bangalore, Karnataka, India Google Scholar More about the auther

, Mahek Porwal

Department of Pharmacology, KLE College of Pharmacy, Rajajinagar, Bangalore, Karnataka, India Google Scholar More about the auther

DIP: 18.01.082.20241203

DOI: 10.25215/1203.082

ABSTRACT

This review article consists of the functions of opioid receptor binding sites, mainly focusing on mu, kappa, and delta receptors, exemplifying their characters and binding affinities, utilizing a least squares non-linear regression curve fitting program that provides insights on the interaction between opioid and their subtypes. And glutamate receptors particularly the mGlu5 receptor and their role in modulating behaviour and neurobiological responses to substances like amphetamine in preclinical and clinical study. Further of the side effects of cannabis on autism symptoms revealing promising outcomes with observable improvements in various domains and around 4% reported side effects. Overall, this systematic review contains the basic information on all the receptors present in the brain including their subtypes, their location, and function. Information of opioid, glutamate and cannabis receptors in detail.

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Babiker Bashir Haroun Baraka @ bashirbaraka118@gmail.com

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ISSN 2348-5396

ISSN 2349-3429

18.01.082.20241203

10.25215/1203.082

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Published in   Volume 12, Issue 3, July-September, 2024